Infectious Diseases Database
"Smarter Diagnosis Starts Here"
About us
IDdx is a clinical decision-support software designed to assist healthcare professionals in diagnosing infectious diseases through intelligent, symptom-based querying. Acting like a searchable, interactive textbook, it allows users to generate and intersect lists of diseases based on specific clinical signs and epidemiological factors for example, identifying infections linked to both abdominal pain and animal bites.

Dengue and Zika Testing for Patients at Risk with Compatible Symptoms
Dengue and Zika are closely related mosquito-borne flaviviruses, sharing similar transmission patterns across tropical and subtropical regions and causing overlapping symptoms such as fever, rash, myalgia, and arthralgia. For patients suspected of having either infection, nucleic acid amplification tests (NAATs) are the preferred diagnostic approach. While IgM antibody tests can help detect additional cases, interpreting results can be challenging due to cross-reactivity and uncertainty in pinpointing the exact timing of infection.
These challenges are particularly significant in pregnant individuals, where distinguishing whether a Zika infection occurred during pregnancy is crucial. This summary outlines updated CDC guidance for diagnostic testing in patients presenting with clinically compatible illness and recent exposure in areas with known circulation of both pathogens. Recommendations for screening asymptomatic pregnant women remain unchanged. For symptomatic nonpregnant individuals, NAATs should be performed on serum samples collected within 7 days of symptom onset.
Evaluating Alpha-Defensin Accuracy for Diagnosing Periprosthetic Joint Infection in Patients with Inflammatory Diseases
The alpha-defensin take a look at has been reported to have excessive accuracy to diagnose periprosthetic joint an infection (PJI). There are remaining considerations in regards to the utility of the take a look at in sufferers with inflammatory illnesses.
Instances with inflammatory illnesses who acquired a 1-stage revision arthroplasty, the primary stage of 2-stage revision arthroplasty, or irrigation and debridement with accessible preoperative alpha-defensin outcomes had been included. Sufferers who acquired a second-stage process, spacer alternate, who had inadequate Musculoskeletal An infection Society standards, or with early postoperative PJI had been excluded from this research. Instances had been categorised as contaminated or not in response to Musculoskeletal An infection Society standards. A complete of 41 instances met the inclusion standards.
Diagnostic and therapeutic strategy to infectious illnesses in strong organ transplant recipients.
Prognosis of strong organ transplant (SOT) recipients has improved, primarily due to higher prevention of rejection by immunosuppressive therapies. Nevertheless, SOT recipients are extremely inclined to standard and opportunistic infections, which symbolize a significant reason for morbidity, graft dysfunction and mortality.Narrative evaluate.We cowl the present epidemiology and primary facets of infections in SOT recipients together with danger components equivalent to postoperative dangers and particular dangers for various transplant recipients, key factors on anti-infective prophylaxis in addition to diagnostic and therapeutic approaches.
We offer an up-to-date information for administration of the primary syndromes that may be encountered in SOT recipients together with acute respiratory failure, sepsis or septic shock, and central nervous system infections in addition to bacterial infections with multidrug-resistant strains, invasive fungal illnesses, viral infections and fewer frequent pathogens which will affect this affected person inhabitants.We offer state-of the artwork evaluate of accessible data of critically unwell SOT sufferers with infections.
The Orchid Concept
A major challenge in dengue management in resource-limited settings is confirming the diagnosis. Clinical features of dengue often overlap with other infections, and molecular diagnostic tools are not readily available to clinicians in many hospitals. Additionally, predicting plasma leakage in dengue remains difficult. Hematocrit levels and ultrasound scans, combined with clinical parameters, are useful for detecting plasma leakage only after it has occurred, not before.
A prospective cohort study of clinically suspected adult dengue patients recruited within the first three days of fever aimed to: a) identify clinical and basic laboratory parameters to distinguish dengue from non-dengue fever; b) evaluate the comparative efficacy of loop-mediated isothermal amplification (LAMP) for dengue diagnosis versus NS1 antigen test and RT-qPCR; and c) identify early markers predictive of plasma leakage or severe dengue. The basic laboratory tests considered included hematological parameters, serum biochemistry, and inflammatory markers.
Only about 70% of clinically suspected patients were confirmed as having dengue by either NS1 antigen test or RT-qPCR. Using a Bayesian latent class model assuming no “gold standard,” LAMP performed equally or better than RT-qPCR and NS1 antigen test, respectively.
When confirmed dengue patients were compared with others, the former group had significantly lower lymphocyte counts and higher aspartate aminotransferase (AST) levels within the first three days of fever. Confirmed dengue patients who developed plasma leakage were younger on average and had higher baseline AST levels compared to those without plasma leakage (p < 0.05).
Clinical suspicion tends to overestimate the true number of dengue cases. RT-LAMP is a promising, low-cost diagnostic tool for dengue detection. Confirmed dengue patients showed higher early AST levels and lower lymphocyte counts compared to others. Among confirmed cases, younger age and higher AST levels early in infection were associated with subsequent plasma leakage.
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Professional healthcare providers dedicated to infectious disease management and patient care.
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Infectious Disease Specialists
Our dedicated team provides personalized care plans, ensuring a smooth recovery process for all patients.
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A comprehensive approach to managing infections, tailored to each patient's needs.
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Enhance your health with our comprehensive infectious disease services. We offer a range of treatments that prioritize your well-being and recovery.

Global Health Services
Providing timely care with our rapid response service for infectious diseases.
Meet the Healthcare Team
Dr. Tony Fred, Medical Director
Dr. Alex Johnson leads the clinical team with expertise and compassion.
Dr. Emily Carter, Medical Director
Dr. Carter ensures that every aspect of care is seamless.
Dr. Aline Turner, Infectious Disease Specialist
Dr. Aline is the expert behind our specialized infectious disease treatments.
John Smith, Patient Coordinator
Our clinic ensures that each patient receives exceptional care.
Our Services
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